Anyone jumping on board now will lose their shirts as they have well and truly missed the Boom.😐 Like the tech dot.com bubble, by the time the opportunity was perceived at ground level, the bubble was bursting.😐😉
The pivot I believe the Pharma crowd will be moving to (especially given the growing push back on conventional treatments and tech) will be the traditional medicines- it's primed for pharma take over, given we have only explored 3-20% of ethnobotanics globally, WHO has just convened the 1st global trad medicines convention to help regulate and sustainably develop these systems, and with AI advancements, we can now sequence, process and extract therapeutics from botanicals, faster than ever before.
Especially with new justifications on patents and GMOs being upheld since 2012, allowing modified natural organisms to be patenable😐🤔🤨 Hence, we will see old Pharma pivot into natural medicines and with WHOs help, become "new pharma".🤔😉🤦♀️
"Buckhaults said that vaccinated people need to be tested to see if any of the foreign DNA has integrated into the genome of their stem cells. This is easily detectable because the foreign DNA has a unique signature. "
the article linked above also links to the following paper:
Sequencing of bivalent Moderna and Pfizer mRNA vaccines reveals nanogram to microgram quantities of expression vector dsDNA per dose
"Multiple methods highlight high levels of DNA contamination in the both the monovalent and bivalent vaccines."
..."While the Qubit™ 3 and Agilent Tape Station™ differ on their absolute quantification, both methods demonstrate it is orders of magnitude higher than the EMAs limit of 330ng DNA/ 1mg RNA."
finally, are we playing faucci like semantical games here? whether it was serial passage in humanized mice or using CRISPR to directly cut & paste in new gene sequences - i believe many of us understand what was going on in Ralph Barric's lab + the Wuhan Inst of Virology was gain of function.
similarly, maybe these shots are not designed to change dna - but they are designed to take over normal cellular function to make cells which uptake LNP carrying mRNA into SARS Co V 2 spike protein manufacturers.
mRNA is a short-lived type of RNA with a single purpose, to make a specific protein. It is present(transiently) in all living cells and works with transfer (t) RNA which brings the amino acids to the ribosome where the ribosomal (r) RNA work together to produce the proteins the cells needs for normal function. Of course the vaccine mRNA is there to produce the spike protein, but the short-lived nature of the mRNA means it does not produce spike protein indefinitely. Enzymic dismantling of the mRNA regenerates the component ribonucleotides which can be re-used re-assembled into other mRNA segments normal to cell function.
not piling on, but just sharing the latest of what i am seeing (all thanks for others for their vigilance: researchers, journalists among them). the following research paper demonstrates longer duration of vaccine based spike protein in the body up to 6 months following injection.
I have read papers which indicated mrna can be detected 2-3 months following injection. i will look for those papers and share if/when i find the source.
Detection of recombinant Spike protein in the blood of individuals vaccinated against SARS-CoV-2: Possible molecular mechanisms
quotes from the abstract. the full paper is available via the above link.
PURPOSE:
The SARS-CoV-2 pandemic prompted the development and use of next-generation vaccines. Among these, mRNA-based vaccines consist of injectable solutions of mRNA encoding for a recombinant Spike, which is distinguishable from the wild-type protein due to specific amino acid variations introduced to maintain the protein in a prefused state. This work presents a proteomic approach to reveal the presence of recombinant Spike protein in vaccinated subjects regardless of antibody titer.
Results
The specific PP-Spike fragment was found in 50% of the biological samples analyzed, and its presence was independent of the SARS-CoV-2 IgG antibody titer. The minimum and maximum time at which PP-Spike was detected after vaccination was 69 and 187 days, respectively.
Conclusions and clinical relevance
The presented method allows to evaluate the half-life of the Spike protein molecule “PP” and to consider the risks or benefits in continuing to administer additional booster doses of the SARS-CoV-2 mRNA vaccine. This approach is of valuable support to complement antibody level monitoring and represents the first proteomic detection of recombinant Spike in vaccinated subjects.
from an article published by the Epoch Times on this research paper:
Based on the results of the study, researchers suggested three possible hypotheses to explain why synthetic spike protein persisted in the vaccinated:
The mRNA from COVID-19 vaccines may be integrated or retranscribed in some cells.
Pseudouridines at a particular sequence position may induce the formation of a spike protein, although the researchers stated this was a remote possibility.
The mRNA-containing nanoparticles may be picked up by bacteria ordinarily present at the basal level in the blood and produce spike protein.
This sounds unlikely as mRNA is short lived and the component ribonucleosides are re used to make other mRNAs, as required by normal cell function. Transcription of DNA into RNA is a normal part of cell function, then the 3 types of RNA go into action making proteins. Transfer t-RNA brings amino acids to the ribosome, where ribosomal r-RNA makes the proteins required according to the sequencing instructions coded for by messenger m-RNA. This knowledge has been around for 50-60 years.
"All recipients have been blinded to the complete ingredient list no one knows exactly what has been injected into the human body. There are some fundamental points known about mRNA. Natural RNA is made of two purines adenine and guanine and two pyrimidines cytosine and uracil. The replacement of uracil with its ribose ring (uridine) with N-1-methyl-pseudouridine, a synthetic product makes the genetic code for the Wuhan Spike protein better stabilized on lipid nanoparticles, long-lasting, and very efficient in terms of evading cellular destruction and able to undergo repeat reading by ribosomes for continued protein synthesis. Morais et al indicate that both Pfizer and Moderna chose development strategies replacing all uridine units with pseudouridine, making the entire strand completely “unnatural” to the human body. Thus vaccine consultants, companies, and patients unfortunately gambled on how long mRNA would be active within the human body."
...
"Fertig et al found lipid nanoparticles with mRNA were measurable in plasma for—15 days. Recently, Castruita et al demonstrated mRNA in blood out to 28 days. Roltgen et al have found mRNA in lymph nodes 60 days after injection. None of these studies demonstrated complete clearance of mRNA from a group of patients. "
i think the link above is a worth a read. as you can see in my quotations, McCullough cites multiple papers demonstrating that the shots' mRNA remains detectable in the human body long after CDC/NIH/FDA said it would be eliminated.
I am not a great fan of the LNP ultra-refrigerated approach. The viral vector approach has greater physicochemical stability and is capable of transport at normal refrigeration temperatures, therefore suitable for wider use geographically.
another unfortunate lie is: the injection stays at the injection site / in the deltoid.
this claim was made extensively despite extensive earlier research al be it in mouse models - which showed within hours of injection LNPs spread systemic wide in the animals.
now there is a growing body of evidence the mrna carrying LNPs can be shared by injection recipient to sexual partners (look up pfizer's clinical protocol in which it compels patients to avoid sexual contact with their partners following administration of the shot for a period of time) or in the case of nursing mothers-to their infants.
Thanks for your reply. It would seem the issue is a quality/purity problem in manufacture, which needs to be improved, not how the mRNA it contains works. RNA only makes changes to DNA if reverse transcriptase is present, eg in a retrovirus, like HTLV-1 which causes leukaemia, or HIV, which causes AIDS.
Anyone jumping on board now will lose their shirts as they have well and truly missed the Boom.😐 Like the tech dot.com bubble, by the time the opportunity was perceived at ground level, the bubble was bursting.😐😉
The pivot I believe the Pharma crowd will be moving to (especially given the growing push back on conventional treatments and tech) will be the traditional medicines- it's primed for pharma take over, given we have only explored 3-20% of ethnobotanics globally, WHO has just convened the 1st global trad medicines convention to help regulate and sustainably develop these systems, and with AI advancements, we can now sequence, process and extract therapeutics from botanicals, faster than ever before.
Especially with new justifications on patents and GMOs being upheld since 2012, allowing modified natural organisms to be patenable😐🤔🤨 Hence, we will see old Pharma pivot into natural medicines and with WHOs help, become "new pharma".🤔😉🤦♀️
#itsonlyjustbegun #oldisnew #naturevspatent
Makes sense to rename as these are not DNA altering, gene editing therapies.
respectfully, are you sure about that?
see this article: Researchers “alarmed” to find DNA contamination in Pfizer covid-19 vaccine
https://maryannedemasi.substack.com/p/researchers-alarmed-to-find-dna-contamination?utm_source=profile&utm_medium=reader2
"Buckhaults said that vaccinated people need to be tested to see if any of the foreign DNA has integrated into the genome of their stem cells. This is easily detectable because the foreign DNA has a unique signature. "
the article linked above also links to the following paper:
Sequencing of bivalent Moderna and Pfizer mRNA vaccines reveals nanogram to microgram quantities of expression vector dsDNA per dose
link: https://osf.io/b9t7m/
from the Discussion section:
"Multiple methods highlight high levels of DNA contamination in the both the monovalent and bivalent vaccines."
..."While the Qubit™ 3 and Agilent Tape Station™ differ on their absolute quantification, both methods demonstrate it is orders of magnitude higher than the EMAs limit of 330ng DNA/ 1mg RNA."
finally, are we playing faucci like semantical games here? whether it was serial passage in humanized mice or using CRISPR to directly cut & paste in new gene sequences - i believe many of us understand what was going on in Ralph Barric's lab + the Wuhan Inst of Virology was gain of function.
similarly, maybe these shots are not designed to change dna - but they are designed to take over normal cellular function to make cells which uptake LNP carrying mRNA into SARS Co V 2 spike protein manufacturers.
all ears to your thoughts.
mRNA is a short-lived type of RNA with a single purpose, to make a specific protein. It is present(transiently) in all living cells and works with transfer (t) RNA which brings the amino acids to the ribosome where the ribosomal (r) RNA work together to produce the proteins the cells needs for normal function. Of course the vaccine mRNA is there to produce the spike protein, but the short-lived nature of the mRNA means it does not produce spike protein indefinitely. Enzymic dismantling of the mRNA regenerates the component ribonucleotides which can be re-used re-assembled into other mRNA segments normal to cell function.
not piling on, but just sharing the latest of what i am seeing (all thanks for others for their vigilance: researchers, journalists among them). the following research paper demonstrates longer duration of vaccine based spike protein in the body up to 6 months following injection.
I have read papers which indicated mrna can be detected 2-3 months following injection. i will look for those papers and share if/when i find the source.
Detection of recombinant Spike protein in the blood of individuals vaccinated against SARS-CoV-2: Possible molecular mechanisms
link: https://onlinelibrary.wiley.com/doi/10.1002/prca.202300048
quotes from the abstract. the full paper is available via the above link.
PURPOSE:
The SARS-CoV-2 pandemic prompted the development and use of next-generation vaccines. Among these, mRNA-based vaccines consist of injectable solutions of mRNA encoding for a recombinant Spike, which is distinguishable from the wild-type protein due to specific amino acid variations introduced to maintain the protein in a prefused state. This work presents a proteomic approach to reveal the presence of recombinant Spike protein in vaccinated subjects regardless of antibody titer.
Results
The specific PP-Spike fragment was found in 50% of the biological samples analyzed, and its presence was independent of the SARS-CoV-2 IgG antibody titer. The minimum and maximum time at which PP-Spike was detected after vaccination was 69 and 187 days, respectively.
Conclusions and clinical relevance
The presented method allows to evaluate the half-life of the Spike protein molecule “PP” and to consider the risks or benefits in continuing to administer additional booster doses of the SARS-CoV-2 mRNA vaccine. This approach is of valuable support to complement antibody level monitoring and represents the first proteomic detection of recombinant Spike in vaccinated subjects.
from an article published by the Epoch Times on this research paper:
Based on the results of the study, researchers suggested three possible hypotheses to explain why synthetic spike protein persisted in the vaccinated:
The mRNA from COVID-19 vaccines may be integrated or retranscribed in some cells.
Pseudouridines at a particular sequence position may induce the formation of a spike protein, although the researchers stated this was a remote possibility.
The mRNA-containing nanoparticles may be picked up by bacteria ordinarily present at the basal level in the blood and produce spike protein.
This sounds unlikely as mRNA is short lived and the component ribonucleosides are re used to make other mRNAs, as required by normal cell function. Transcription of DNA into RNA is a normal part of cell function, then the 3 types of RNA go into action making proteins. Transfer t-RNA brings amino acids to the ribosome, where ribosomal r-RNA makes the proteins required according to the sequencing instructions coded for by messenger m-RNA. This knowledge has been around for 50-60 years.
i wish what you wrote is true, but it appears there has been a slight of hand / obfuscation with this product.
from Peter McCullough -
https://petermcculloughmd.substack.com/p/critical-role-of-pseudouridine-in?utm_source=%2Fsearch%2Furodine&utm_medium=reader2
"All recipients have been blinded to the complete ingredient list no one knows exactly what has been injected into the human body. There are some fundamental points known about mRNA. Natural RNA is made of two purines adenine and guanine and two pyrimidines cytosine and uracil. The replacement of uracil with its ribose ring (uridine) with N-1-methyl-pseudouridine, a synthetic product makes the genetic code for the Wuhan Spike protein better stabilized on lipid nanoparticles, long-lasting, and very efficient in terms of evading cellular destruction and able to undergo repeat reading by ribosomes for continued protein synthesis. Morais et al indicate that both Pfizer and Moderna chose development strategies replacing all uridine units with pseudouridine, making the entire strand completely “unnatural” to the human body. Thus vaccine consultants, companies, and patients unfortunately gambled on how long mRNA would be active within the human body."
...
"Fertig et al found lipid nanoparticles with mRNA were measurable in plasma for—15 days. Recently, Castruita et al demonstrated mRNA in blood out to 28 days. Roltgen et al have found mRNA in lymph nodes 60 days after injection. None of these studies demonstrated complete clearance of mRNA from a group of patients. "
i think the link above is a worth a read. as you can see in my quotations, McCullough cites multiple papers demonstrating that the shots' mRNA remains detectable in the human body long after CDC/NIH/FDA said it would be eliminated.
I am not a great fan of the LNP ultra-refrigerated approach. The viral vector approach has greater physicochemical stability and is capable of transport at normal refrigeration temperatures, therefore suitable for wider use geographically.
another unfortunate lie is: the injection stays at the injection site / in the deltoid.
this claim was made extensively despite extensive earlier research al be it in mouse models - which showed within hours of injection LNPs spread systemic wide in the animals.
now there is a growing body of evidence the mrna carrying LNPs can be shared by injection recipient to sexual partners (look up pfizer's clinical protocol in which it compels patients to avoid sexual contact with their partners following administration of the shot for a period of time) or in the case of nursing mothers-to their infants.
https://www.igor-chudov.com/p/covid-vaccine-sheds-in-breast-milk?utm_source=post-email-title&publication_id=441185&post_id=137202408&utm_campaign=email-post-title&isFreemail=true&r=5ah2c&utm_medium=email
Thanks for your reply. It would seem the issue is a quality/purity problem in manufacture, which needs to be improved, not how the mRNA it contains works. RNA only makes changes to DNA if reverse transcriptase is present, eg in a retrovirus, like HTLV-1 which causes leukaemia, or HIV, which causes AIDS.